With Professor Jean-Bernard Fourtillan we put an end to the aluminium in human medicines scandal Professor Jean-Bernard Fourtillan discovered the Sleepwatch system and its many therapeutic applications in the form of patches. At the same time, he ...
Letter from Pr Henri Joyeux no 154
Until the sleep-wake system was discovered, the cause of the paradoxical adverse effects of benzodiazepines and related drugs was unknown. The listing in the official journal of 10 January 2017 of Zolpidem (Stilnox and its generic equivalents) as a narcotic drug is an opportunity to explain why all these sleeping pills and anti-anxiety drugs are narcotics. They have unacceptable adverse effects, known as “paradoxical”, as they actually exacerbate the effects they are supposed to treat.
As we will explain, benzodiazepines and related drugs are in fact psychostimulants, which is why they are considered narcotics.
Before you read this letter dedicated to the problems posed by the use of benzodiazepines and related drugs in the treatment of sleep disorders and anxiety, we recommend that you watch the following video: “Sleep disorders and how to treat them”, Pr J.B. Fourtillan and Pr H. Joyeux (YouTube: duration 16 min 25).
Letter from Pr Henri Joyeux no 150
This new letter explains to you how depression will be treated better with transdermal administration of the 2 pineal sleep and wake hormones.
We are embarking on a new therapeutic course.
We are already well aware of the obstacles that await us. We do not fear them, because they are in service of the general public.
French physicians are the world champions of prescribing antidepressants. Beyond this excessive prescribing, undoubtedly encouraged by pharmaceutical Laboratories, they should know that, on the pretext of helping patients sleep better, soporific and anxiolytic medicines, i.e. benzodiazepines and related drugs (such as Stilnox®), should never be prescribed to a patient taking antidepressants.
Antidepressants and sleeping pills are incompatible.
No one will be surprised by this, since the health authorities have just classified Zolpidem (Stilnox® and its generics), without also knowing why, in the category of narcotics. However, all narcotics are psychostimulant medicines that, by increasing vigilance and anxiety, maintain and promote nervous breakdowns.
Through Pr Jean-Bernard Fourtillan’s answers you will learn:
– The mechanism of nervous breakdowns, which can be compared to transient sleep disorders.
– By what mechanisms the various types of antidepressants (NRI and SRI) act.
– The characteristics of an ideal antidepressant treatment that does not disturb the sleep-wake cycle and has no undesirable effects.
– Why the dual-compartment transdermal patch, which will separately contain the 2 natural sleep and wake hormones, will constitute the ideal and most natural treatment for nervous breakdown.
– Why Alzheimer’s and Parkinson’s patients have nervous breakdowns, particularly when they learn of the disease of which they are victims.
– When the transdermal patch will be made available to patients.
Letter from Pr Henri Joyeux no 147
Sleep which is often disturbed! It affects us all.
This letter, which focuses on sleep, has been eagerly awaited. The general public are passionate about this subject which disrupts so many nights of our contemporaries.
The pace of modern life, sleepless nights, our city thoroughfares lit up like the middle of the day, have made us forget about the importance of nocturnal rest. This is how our body works. It points this out to us when we forget, in the form of insomnia or hypersomnia which combine and cause so many diseases which increasingly affect younger people.
Here is the letter which will give you all the information you need on these key issues discovered at the juncture of the 20th and 21st centuries.
Pr Jean-Bernard Fourtillan discovered the sleep hormone and, as a result, the regulation of the very different conditions of day and night. He agreed to answer my questions.
You will learn about the gland which is the origin of sleep and wake states, its location and the hormones it produces; but also about its mode of action and the plasma marker which, when measured in a small amount of blood, will provide the indication of a hormone replacement by patch to enable the transdermal absorption of the deficient hormones.
Do not hesitate to circulate this letter, intended for the general public, who now have the capacity to understand, as well as scholars and experts in medicine.
Letter from Pr Henri Joyeux no 144 After the detailed presentation, by James Parkinson and Alois Alzheimer themselves, of the diseases named after them, here is a second fictional interview conducted by James and Alois. They talk to Professor Jea...
Letter from Pr Henri Joyeux no 142
In this letter, to facilitate understanding, we have devised a dialogue between James Parkinson and Alois Alzheimer. They interview Professor Jean-Bernard Fourtillan who discovered the sleep hormone, as well as sleep-wake regulation.
After the detailed presentation, by James Parkinson and Alois Alzheimer themselves, of the diseases named after them, here is a first fictional interview conducted by James and Alois. They talk to Professor Jean-Bernard Fourtillan, who discovered the sleep hormone and the sleep-wake regulation.
These two neurodegenerative diseases share the same cause which can affect different regions of the brain: the secretions of the 3 pineal hormones, Melatonin, 6-Methoxyharmalan and Valentonin are insufficient.
Pr Jean-Bernard Fourtillan explains in detail the action of the 3 hormones produced by the small pineal gland at the centre of the brain, also known as epiphysis. Discharged into the blood stream during the night, they are distributed throughout the body and make their way to their sites of action. Melatonin protects all cells, more specifically the nerve cells (neurons), by reducing oxygenated free radicals, which prevents their destruction via radical oxidation processes.
The other 2 pineal hormones, Valentonin (VLT) and 6-Methoxyharmalan (6-MH), modulate the responses of 2 types of specific receptors:
– the receptors of the neurotransmitters located on synapses, junction points between the neurons. They amplify (VLT) or reduce (6-MH) the transmission of nerve impulses in these neurons;
– and the hormone receptors (receptors of liberins or stimulines) located on the endocrine glands (hypophysis, etc.). VLT reduces hormonal secretions during the night, unlike 6-MH, which reduces them during the day.
Thanks to their competing actions, in waking or sleeping mode, VLT and 6-MH totally regulate the life of our body 24 hours a day.
The discovery of these regulation mechanisms helps explain the effectiveness of the substitution treatment which provides the 3 hormones of the sleep-wake regulation, in the prevention and treatment of neurological disorders.
Letter from Pr Henri Joyeux no 139
In his letter to all those affected by Parkinson’s disease, Pr Henri Joyeux gets the father of the disease himself to talk. How did he discover and describe it? Why is it named after him? Why are the numerous treatments proposed to patients relatively ineffective, even at the onset of the disease, and why does the body become resistant to them?
James Parkinson presents the discovery made in France by Pr Jean-Bernard Fourtillan, a professor of medicinal chemistry. It relates to the regulation of the Sleep-Wake system, which is the responsibility of the pineal gland, aka epiphysis. The deregulation of this system causes all the disorders of the disease, in the centre of the brain, in the basal ganglia. Incredible therapeutic prospects for tens of millions of people worldwide.